What is Cannabinoid Hyperemesis Syndrome CHS?

Among the leading suspects, he says, are lack of sleep and intense stress. CHS may be related to an imbalance in the body’s communication system—the hypothalamic-pituitary-adrenal (HPA) axis—which regulates stress responses,” says Andrews. “The brain’s endocannabinoid system modulates the stress response, and cannabis makes that pendulum swing further one way than the other,” which can trigger symptoms. Abstaining for a few weeks or months will temporarily halt all symptoms, as soon as the user goes back to using cannabis, the symptoms will begin again. Sometime in 2018, a study stated that a visit to the emergency room for a CHS-related diagnosis could cost as much as $4,600 for an average patient. CHS is a disease that causes marijuana users to experience high sensitivity to cannabinoid compounds —especially THC.

Behavioral Health

One study looking at Reddit posts on the subject found that spicy food, greasy food, coffee, black tea, and alcohol were frequently mentioned as CHS triggers. If you have symptoms, your doctor will do a physical exam and ask for your detailed medical history. Let your doctor know how much marijuana you use and how often you use it.

Infant and Child Health

• A Doctor’s advice should be sought before using this product.
• It tends to affect people who use cannabis at least once a week and happens more often in adults who’ve been using cannabis since their adolescent years.
• For example, if you smoke weed, eat edibles, use tinctures, or dab or vape THC, tell your doctor about any or all of them.
• People with CHS usually have a long history of marijuana use.
• Smoking extra marijuana won’t help your nausea but will make it worse.
• “We give patients IVs to hydrate them. We do basic testing, just to make sure their kidneys aren’t failing, that their electrolytes are not very disturbed,” he said.

Early recognition of CHS is essential to prevent complications related to severe volume depletion. The recent body of research recognizes that patients with CHS impose a burden on the healthcare systems. Understanding the pathophysiology of the endocannabinoid system (ECS) remains central in explaining the clinical features and potential drug targets for the treatment of CHS. The frequency and prevalence of CHS change in accordance with the doses of tetrahydrocannabinol and other cannabinoids in various formulations of cannabis. CHS is unique in presentation, because of the cannabis’s biphasic effect as anti-emetic at low doses and pro-emetic at higher doses, and the association with pathological hot water bathing. Cannabinoid hyperemesis syndrome (CHS) is a (probably) rare syndrome that occurs in frequent and chronic cannabis users.

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“We give patients IVs to hydrate them. We do basic testing, just to make sure their kidneys aren’t failing, that their electrolytes are not very disturbed,” he said. “But really, to cure them of this condition, they need to stop smoking.” After two weeks in the hospital with no diagnosis, Hagler chs cannabis said she was told by doctors she was suffering from a neurological or psychological disorder.

What is the treatment for cannabinoid hyperemesis treatment?

• With the widespread use, increased potency and legalization of marijuana in multiple states in the U.S., CHS may be becoming increasingly common.
• Some have suggested that high doses might cause the anti-emetic effects to flip into a pro-emetic syndrome.
• It can take days to months to resolve but most patients recover once they are fully off of any kind of cannabinoid.

This is a recently discovered disease condition that occurs in people that affects habitual consumers of cannabis. TRPV1 receptor overstimulation – THC activates the same receptors as capsaicin, explaining the relief from hot showers. Pancreatitis – Inflammation of the pancreas causing severe abdominal pain and nausea. In one small study of eight patients hospitalized with CHS, four of the five who stopped using weed recovered from CHS. One of the 4 who recovered went back to using marijuana and the vomiting resumed. Not everyone with the condition seeks medical help or tells their provider that they use marijuana.

Recovery stage

• The team extracted the genetics of 28 patients that have previously been diagnosed with CHS.
• Hagler, who has been cannabis-free for five years, said she started a Facebook group to help others who say they are dealing with the condition.
• During the hyperemesis stage, doctors focus on preventing dehydration and stopping the symptoms of nausea and vomiting.
• Although this information comes from case reports, doctors can use these criteria to diagnose the condition more quickly.
• While some reports indicate temporary symptomatic relief with scalding hot showers or a heating pad, stopping marijuana use is the most successful way to manage the condition, experts say.

Cannabis hyperemesis syndrome (CHS) is a form of functional gut-brain axis disorder characterized by bouts of episodic nausea and vomiting worsened by cannabis intake. It is considered as a variant of cyclical vomiting syndrome seen in cannabis users especially characterized by compulsive hot bathing/showers to relieve the symptoms. CHS was reported for the first time in 2004, and since then, an increasing number of cases have been reported. With cannabis use increasing throughout the world as the threshold for legalization becomes lower, its user numbers are expected to rise over time. Despite this trend, a strict criterion for the diagnosis of CHS is lacking.

• For example, the drug affects the receptors in the esophageal sphincter, the tight band of muscle that opens and closes to let food go from your throat to your stomach.
• Although medicine doesn’t yet know what causes CHS, something in cannabis appears to be the culprit.
• Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the main cannabinoids in marijuana products.

For those who use cannabis for medical reasons, discussing alternative treatments with healthcare providers is crucial. CHS is also underdiagnosed because people sometimes use marijuana to suppress nausea and vomiting. Doctors currently lack knowledge of the condition, and there are no clinical guidelines for its what is Oxford House treatment and management. Soon after, Hagler learned about CHS, cannabinoid hyperemesis syndrome, which affects people who use high doses of marijuana daily over an extended period of time.